cocaine

Anyone who watched TV in the 1980s know what a brain on drugs looks like. 

According to recent research out of Johns Hopkins, the reality of a drug-addicted brain might be even uglier than that. The researchers found that high doses of cocaine caused brain cells to cannibalize themselves through a process known as autophagy โ€” in other words, yes, cocaine eats holes in your brain.

โ€œA cell is like a household that is constantly generating trash,โ€ the studyโ€™s lead author, Prasun Guha, said. โ€œAutophagy is the housekeeper that takes out the trashโ€”itโ€™s usually a good thing. But cocaine makes the housekeeper throw away really important things, like mitochondria, which produce energy for the cell.โ€

The study also found a possible treatment to prevent that kind of cell death โ€” but the simpler solution is to just not do high doses of cocaine.