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For the second time in as many years, insult comic Lisa Lampanelli will come to town and perform, not at a club or one of the big halls that sometimes host stand-up comedy but at Center Stage, the State Theater of Maryland.

Last December, Lampanelli performed a reading of the play “White Rabbit Red Rabbit,” and this November, she’s bringing an original 90-minute show, “Losin’ It,” that features a cast of actors and stories about weight loss and body image.

“Hey, if Oprah–the most powerful woman in the world–still struggles with her weight, what hope do Pam from Accounting, Joyce the security guard, or Lisa the comedian have?!?” the comic said in a statement. “When you think about it, we have no choice but to laugh!”

The Grammy-nominated comedian previously tackled her own 100-pound weight loss in the off-Broadway play “Stuffed.”

Tickets for the one-time show, scheduled for Nov. 17, are on sale now and range from $35-$100.

Brandon Weigel is the managing editor of Baltimore Fishbowl. A graduate of the University of Maryland, he has been published in The Washington Post, The Sun, Baltimore Magazine, Urbanite, The Baltimore...